Search Results
4 results for search term 'Ai9' in category Delivery System
AAV+Focused UltrasoundDelivery System - [In Vivo] [Delivery Systems Initiative] [Mouse]Show Experiments (1) |
RNP-NC-RVGDelivery System - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] |
RNP-NC-CPPDelivery System - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Collaborative Opportunity Fund, Delivery Systems Initiative] [Human, Mouse]Show Experiments (5)
Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain.
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RNP-NC-no ligandDelivery System - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Collaborative Opportunity Fund, Delivery Systems Initiative] [Human, Mouse]Show Experiments (3)
Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain.
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4 results for search term 'Ai9' in category Delivery System
Type | Subtype | Name | Description | Source | View Associated.. |
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Viral vector | Adeno Associated Virus | AAV+Focused Ultrasound | See vector details | Leong Lab |
Show Experiments (1) |
Nanoparticle | Polymer-RNP nanocapsule | RNP-NC-RVG | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a RVG peptide YTIWMPENPRPGTPCDIFTNSRGKRASNG which specifically interacts withthe N-acetylecholine receptor (AchR) on neuronal cells, which mediates NP entry | Gong Lab | |
Nanoparticle | Polymer-RNP nanocapsule | RNP-NC-CPP | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. This nanoparticle has an addition of a cell penetrating peptide (CPP) from the TAT peptide (GRKKRRQRRRPQ) which lacks cell-type specficity | Gong Lab |
Show Experiments (5)
Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain.
|
Nanoparticle | Polymer-RNP nanocapsule | RNP-NC-no ligand | The nanocapsule is a thin glutathione (GSH)-cleavable covalently crosslinked polymer coating around a preassembled ribonucleoprotein (RNP) complex between a Cas9 nuclease and an sgRNA. | Gong Lab |
Show Experiments (3)
Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain.
|